Emergent Radiotherapy for Leukemia-Induced Cranial Neuropathies Refractory to Intrathecal Therapy
نویسندگان
چکیده
منابع مشابه
Low incidence of CNS relapse with cranial radiotherapy and intrathecal methotrexate in acute lymphoblastic leukemia.
OBJECTIVES To assess the incidence of isolated central nervous system (CNS) relapses in patients of acute lymphoblastic leukemia (ALL) treated with a protocol containing cranial irradiation and intrathecal methotrexate as CNS directed therapy. DESIGN Prospective non randomized study. SETTING Department of Medical Oncology, Tata Memorial Hospital. SUBJECTS 623 children of ALL on MCP 841. ...
متن کاملCranial neuropathies, confusion, and ataxia— Challenges for diagnosis and therapy
Introduction: The differential diagnosis of patients presenting with multiple cranial neuropathies, ataxia, and altered mentation is broad and includes immunologic, infectious, vasculitic and metabolic conditions. Primary considerations are Bickerstaff’s brainstem encephalitis (BBE), the Miller Fisher syndrome (MFS), Wernicke’s encephalopathy and botulism. The initial workup may be unrevealing....
متن کاملMultiple cranial neuropathies.
Patients presenting with multiple cranial neuropathies are not uncommon in neurologic clinical practice. The evaluation of these patients can often be overwhelming due to the vast and complicated etiologies as well as the potential for devastating neurologic outcomes. Dysfunction of the cranial nerves can occur anywhere in their course from intrinsic brainstem dysfunction to their peripheral co...
متن کاملMultiple cranial neuropathies
There are several syndromes of multiple cranial nerve involvement. One syndrome described by Garcin was a step-b-step ipsilateral involvement of all 12 cranial nerves unilaterally. This term is now used for multiple cranial nerve palsies that do not fit into any of the other named syndromes. This article describes the various pathologies associated with multiple cranial nerve palsies and their ...
متن کاملDiplopia due to ocular motor cranial neuropathies.
PURPOSE OF REVIEW Determining which cranial nerve(s) is (are) involved is a critical step in appropriately evaluating a patient with diplopia. RECENT FINDINGS New studies have looked at the various etiologies of cranial nerve palsies in the modern imaging era. The importance of the C-reactive protein test in evaluating the possibility of giant cell arteritis has recently been emphasized. SU...
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ژورنال
عنوان ژورنال: Cureus
سال: 2021
ISSN: 2168-8184
DOI: 10.7759/cureus.15212